Immunocytochemical Localization Of The Neural Cell Adhesion Molecules L1, N

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• After transection or crush of the sciatic nerve, L1 disappeared from the corpuscles however reappeared with regrowing axons at contact websites between axonal membranes and inside core cells.
• In adult corpuscles, L1 was present solely at contact sites between the sensory axon and inner core lamellae.
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In adult corpuscles, L1 was current solely at contact websites between the sensory axon and internal core lamellae. From delivery, the earliest stage examined, till day 7, L1 was additionally expressed on lamellar processes of the inner core cells. J1/tenascin was found only in affiliation with the extracellular material of the inner core, particularly with the two radial clefts and the boundary area between inner and outer core. In creating corpuscles, J1/tenascin became detectable on extracellular material with the onset of internal core differentiation at approximately day 2. After transection or crush of the sciatic nerve, L1 disappeared from the corpuscles however reappeared with regrowing axons at contact sites between axonal membranes and internal core cells.

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